Prunus divaricata var (yonuz erik) metanol ekstraktının toplam fenolik bileşik ve toplam antioksidan/oksidan kapasitesinin araştırılması

Detection of bioactive compounds that determine the antioxidant capacity of naturally grown plants may provide their use in the treatment of oxidative stress-related diseases. Plants grown at high altitudes, such as Prunus divaricata var (locally known as yonuz plum, wild plum, dolphin plum, and sour plum) have high nutritional value, disease-reducing and therapeutic potential. In this study, total antioxidant capacity (TAC), total oxidant capacity (TOC), oxidative stress index (OSI) and total polyphenolic compound (TPC) contents of methanol extract were determined and their therapeutic potential was evaluated. The fruits were collected in September and dried at room temperature and in a free environment for an average of 20 days. Dried fruits (10 g) were
dissolved in methanol (500 mL), and their total antioxidant/oxidant
capacity was determined by extraction and evaporation. TPC was
measured spectrophotometrically using the Folin-Ciocalteu reagent
method. In conclusion, the TAC level of the wild plum fruit extract was
3.595±0.05 mmol Trolox equiv./L, the TOC level was 15.853±0.09 μmol
H2O2 Equiv./L and OSI 0.441±0.006 (AU), and the total TPC content was
41.52 ± 0.17 mg GAE g-1
. P. divaricata is rich in phenolic compounds and
has a strong antioxidant and oxidant activity. We believe that many
antioxidant compounds can have a pro-oxidant effect as a result of their
interaction with each other. The strong oxidant activity of P. divaricata
should be carefully evaluated for nutritional and therapeutic use.